According to the A.C.O.G. committee, there is a significant cost difference between misoprostol [trade name = Cytotecl] and dinoprostone [trade name = Cervidil Prepidil] for induction of labor. The price of a 100-µg tablet of misoprostol may range from $0.36 to $1.20, compared with a dinoprostone gel kit that ranges from $65 to $75 and the dinoprostone vaginal insert that costs approximately $165. The A.C.O.G. committee notes that the cost would increase if oxytocin augmentation [trade name = Pitocin] were needed. In addition, dinoprostone is an unstable compound that requires refrigeration to maintain its potency, whereas misoprostol is stable at room temperature.
- ACOG Technical Bulletin No. 10, 11/99, Obstetrics and Gynecology.
ACOG Practice Guidelines-Induction. American Family Physician, July 15, 2000
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